maf1 — Magnaporthe oryzae 70-15

Summary

MGG_15675 (maf1) in Magnaporthe oryzae 70-15 on chromosome 2 encodes a Maf1 superfamily protein with DNA-binding transcription repressor activity specific to RNA polymerase III, RNA polymerase III core binding, and kinase activity. The gene is associated with negative regulation of transcription by RNA polymerase III, appressorium formation, and DNA-dependent transcription. The protein localises to the nucleolus, cytoplasm, and nucleus. Maf1 is linked to barley (Hordeum vulgare) and rice (Oryza sativa), and to blast disease in rice. Studies of related genes in other species, including Verticillium dahliae and Fusarium oxysporum pathovars, connect the Maf1 family to repression of RNA polymerase III transcription.