MYO2 — Magnaporthe oryzae 70-15

Summary

MoMYO2 (MGG_16213) on chromosome 1 of Magnaporthe oryzae 70-15 encodes Myosin-2, a calcium-dependent ATPase with microfilament motor activity, calmodulin binding, F-actin binding, and small GTPase binding. This myosin is associated with vesicle transport along actin filaments, actin filament bundle organization and retrograde transport, actomyosin contractile ring assembly, endomembrane organization, Golgi division, organelle inheritance including peroxisome and ER inheritance, receptor-mediated endocytosis, intracellular mRNA localization, and asexual reproduction. It localizes to the myosin V complex, myosin filament, cortical cytoskeleton, transport vesicles, and actin filament bundles. The gene is linked to blast disease in rice and to turgor pressure. Phenotypic associations include absent or decreased septum formation, delayed nuclear fusion during mating, abnormal Golgi and vacuolar distribution, decreased budding and cytokinesis, and absent peroxisomal transport.