DBP2 — Magnaporthe oryzae 70-15

Summary

MGG_16901 (DBP2) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with ATP hydrolase activity, RNA helicase activity, and binding capabilities for G-quadruplex DNA, snoRNA, mRNA, and ATP. The gene is associated with alternative mRNA splicing via the spliceosome, nonsense-mediated mRNA decay, nuclear polyadenylation-dependent mRNA catabolism, rRNA processing, RNA 3'-end formation, sexual reproduction, and mating. It localizes to the cytoplasm, nucleus, and ribonucleoprotein complexes. Phenotypic associations include abnormal mitotic recombination, decreased mating-type switching, absent or abnormal sporulation efficiency, altered cell cycle progression (including increased S-phase rate and premature G1/S transition), delayed vegetative and exponential growth, increased thermotolerance and gamma ray resistance, altered chemical resistance, and increased fermentative growth and carbon source utilization.