DBP2 — Magnaporthe oryzae 70-15

Summary

MGG_15532 (DBP2, also known as PRP5) in Magnaporthe oryzae 70-15 on chromosome 2 encodes a DEAD-box RNA helicase with ATP hydrolase and nucleic acid binding activities. The gene is associated with RNA splicing via the spliceosome, major prespliceosome assembly, mRNA processing, digestion, sexual reproduction, and mating. It localises to the nucleus and the major prespliceosome. Phenotypic associations include abnormal mitotic recombination, decreased mating type switching, absent sporulation efficiency, delayed vegetative and exponential growth, increased thermotolerance and gamma ray resistance, altered cell cycle progression (including G1/S and G2/M transitions), increased fermentative growth, and increased carbon source utilization. The gene is linked to over 300 additional phenotypes and 110 related genes, including CRP1, MTM1, and SLX1. Related genes in other species are linked to oxidative stress response.