laeA — Magnaporthe oryzae 70-15

Summary

MGG_15419 (laeA) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a methyltransferase domain-containing protein with SAM-dependent methyltransferase superfamily features and methyltransferase activity. The gene is associated with the regulation of secondary metabolism, including penicillin G anabolism, sterigmatocystin metabolism, and melanin anabolism. It is also linked to appressorium formation, sporulation, ascospore formation, and interaction with the host. Additional associations include signal transduction, DNA-dependent transcription, and methylation processes. The encoded protein localizes to the nucleus. Studies of related genes in other species link the family to secondary metabolite regulation, though this is not established for M. oryzae.