ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_14824) on chromosome 4 of Magnaporthe oryzae 70-15 encodes an ABC-type oligopeptide transporter with ATP-coupled transmembrane transporter activity, ATP hydrolase activity and ATP binding, belonging to the type 1 exporter family. The gene is associated with host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, signal transduction, secondary metabolism, membrane transport, homeostasis, and regulation of cell growth. It is linked to siRNA-mediated post-transcriptional gene silencing, transposition, retrotransposition, translation elongation, and oligopeptide export from the mitochondrion. The product localises to the mitochondrial inner membrane, endomembrane system, plasmalemma, and membrane. Associations with oxidative stress resistance, hypoosmotic stress resistance, endocytosis, vacuolar morphology, pexophagy, cell cycle progression, and prion inheritance have been reported. Related genes in other species link the family to mitochondrial iron-sulfur cluster export and multidrug resistance.