CYS2 — Magnaporthe oryzae 70-15

Summary

MGG_14202 (MoCYS2, CYS2) on chromosome 7 of Magnaporthe oryzae 70-15 encodes a homoserine O-acetyltransferase with L-serine O-succinyltransferase, L-serine O-acetyltransferase, and deacetylcephalosporin-C acetyltransferase activities. The gene is associated with L-methionine biosynthesis, cysteine biosynthesis, homoserine metabolism, and carbon catabolite repression. It is linked to appressorium formation and maturation, regulation of growth, response to oxidative stress, melanin biosynthesis, chitin breakdown, lipolysis, and antibiotic biosynthesis. The encoded protein localises to the mitochondrial lumen and cytosol. Studies of related genes in other species link the family to homoserine O-acetyltransferase activity (EC 2.3.1.31) and L-homoserine O-succinyltransferase activity (EC 2.3.1.175).