ABCA — Magnaporthe oryzae 70-15

Summary

MGG_13624 (MoABCA) on chromosome 4 of Magnaporthe oryzae 70-15 encodes an ABC transporter of the CDR4 type, belonging to the ABCG/PDR family. The gene is associated with ATP binding and hydrolase activity, and its product localises to the plasma membrane and vacuolar membrane. MoABCA is associated with appressorium formation, xenobiotic detoxification via transmembrane export, response to toxic substances, stimulus detection, protein dephosphorylation, hypersensitivity, cell death, and DNA repair. It is also linked to the zearalenone biosynthetic process. Phenotypic associations include abnormal small molecule transport, increased sporulation rate, altered vacuolar distribution and transport, decreased cell death rate, and changes in nutrient uptake, cell cycle progression, and chronological lifespan. Studies of related genes in other species link the family to virulence and pathogenicity.