CHS7 — Magnaporthe oryzae 70-15

Summary

MGG_13014 (MoCHS7, CHS7) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a protein with chitin synthase activity (EC 2.4.1.16), cytoskeletal motor activity, actin binding, and ATP binding, and contains chitin synthase, myosin head motor, DEK_C, and cytochrome b5-like domains. The gene is associated with appressorium formation, chitin anabolism, fungal-type cell wall organization, invasive growth, hyphal growth, and morphogenesis. Its product localizes to the myosin complex, cytoplasmic vesicle membrane, cross wall, cell periphery, cell tip, and plasmalemma. MoCHS7 is linked to turgor pressure. Studies of related genes in other species connect the family to loss of pathogenicity and reduced virulence.