PCT1 — Magnaporthe oryzae 70-15

Summary

MGG_12387 (PCT1, MoPCT1) in Magnaporthe oryzae 70-15 on chromosome 2 encodes an NADH:ubiquinone oxidoreductase-like 20 kDa subunit domain-containing protein, with ubiquinone reductase, quinone binding, 4Fe-4S cluster binding, and redox activities. It is associated with mitochondrial complex I assembly, electron transport coupled proton transport, aerobic respiration, the Kennedy pathway, methionine metabolism, autophagy, and methylation. The gene is linked to decreased oxidative phosphorylation, abnormal cell cycle progression through G1/S, reduced invasive growth, increased sporulation efficiency, decreased osmotic stress resistance, altered carbon and nitrogen source utilization, decreased protein secretion, and abnormal endomembrane system morphology. It is also linked to decreased nucleophagy and micronucleophagy, increased prion formation, and reduced survival in stationary phase.