CTA4 — Magnaporthe oryzae 70-15

Summary

MoCTA4 (CTA4) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a P5A-type ATPase, a member of the P-type ATPase family with E1-E2 ATPase, cation-transporting ATPase, and membrane protein dislocase activities, and binds calcium and ATP. The gene is associated with appressorium formation, spore germination, sporulation, hyphal growth, cell division, and the extraction of mislocalized proteins from the ER membrane. It is linked to calcium ion membrane transport, cellular calcium ion homeostasis, calcium signaling, and the response to unfolded protein. Localization evidence connects the product to the ER, Golgi, vacuolar membrane, and plasma membrane. Phenotypic associations include altered vacuolar transport, decreased micronucleophagy, increased aneuploidy, abnormal colony shape and chitin deposition, and changes in fermentative and anaerobic growth, as well as resistance to desiccation, freeze-thaw, hydrostatic pressure, and alkaline pH.