PCT1 — Magnaporthe oryzae 70-15

Summary

MGG_10805 (PCT1, MoPCT1) in Magnaporthe oryzae 70-15 encodes a protein with an NADH:ubiquinone oxidoreductase-like 20 kDa subunit domain, possessing ubiquinone reductase and 4Fe-4S cluster binding activities. The gene is associated with mitochondrial complex I assembly, electron transport coupled proton transport, aerobic respiration, and localisation to the respiratory chain complex I and mitochondria. It has been linked to diverse phenotypes including decreased oxidative phosphorylation, abnormal cell cycle progression through G1/S phase transition, decreased invasive growth, decreased osmotic stress resistance, altered nutrient and carbon source utilization, decreased autophagy and nucleophagy, increased sporulation efficiency, and decreased survival in stationary phase.