ARF3 — Magnaporthe oryzae 70-15

Summary

MoARF3 (MGG_10676) on chromosome 4 of Magnaporthe oryzae 70-15 encodes an ADP-ribosylation factor 6, a small GTPase of the ARF/SAR family with GTP-binding and GTPase activity. The gene is associated with appressorium formation, host invasion, hyphal growth, and cell growth mode switching from monopolar to bipolar. It is linked to Golgi localization, ER-to-Golgi transport, vesicle transport, endocytosis, protein transport, and tubulin assembly, as well as regulation of mitotic cytokinesis and positive regulation of mitotic entry. Localization evidence connects the product to the Golgi complex, microtubule cytoskeleton, division septum, cell cortex, and plasmalemma. Phenotypic associations include abnormal spore germination, filamentous growth, and bipolar budding pattern, altered cell cycle progression, decreased cytokinesis rate, and changes in protein secretion, redox state, and desiccation resistance. Related genes in other species link the family to EC 3.6.5.2.