ENO1 — Magnaporthe oryzae 70-15

Summary

MoENO1 (ENO1) of Magnaporthe oryzae 70-15 encodes a phosphopyruvate hydratase (enolase, EC 4.2.1.11) that contains enolase and EF-hand calcium-binding domains and binds magnesium. The enzyme is annotated to the glycolytic process, the ER stress response, the cellular response to farnesol, heterotrophy, and cellular osmotic response, and localises to the enolase complex. MoENO1 is associated with numerous phenotypes including normal filamentous growth, increased adhesion, decreased colony size, increased cell death, abnormal cytokinesis, and altered fermentative and respiratory metabolism. It is also linked to prion formation and inheritance, endocytosis, pexophagy, mitochondrial genome maintenance, and hyperosmotic stress resistance. Studies of the enolase family in other species connect related genes to nuclear pore complex components and various metabolic regulators.