OEFC — Magnaporthe oryzae 70-15

Summary

MGG_10422 (MoOEFC) on chromosome 6 of Magnaporthe oryzae 70-15 encodes the C6 transcription factor OefC, a zinc-binding protein with a Zn2Cys6 DNA-binding domain and Fun_TF family domain. It localises to the nucleus and has DNA-binding transcription factor activity, specifically RNA polymerase II-specific cis-regulatory region binding. The gene is associated with positive regulation of transcription by RNA polymerase II, DNA-dependent transcription, appressorium formation, and invasive growth. MoOEFC is linked to blast disease in rice (Oryza sativa). Studies of related genes in other species connect the family to fungal pathogenicity, though this is not established for MoOEFC itself.