OS-5 — Magnaporthe oryzae 70-15

Summary

MoOS-5 (MGG_10268) in Magnaporthe oryzae 70-15 encodes a mitogen-activated protein kinase kinase with dual-specificity protein kinase activity, MAPKK activity, and MAP kinase scaffold activity, and is annotated with Nalpha-acetyltransferase activity. This gene is associated with the positive regulation of appressorium formation, host invasion, and the cell integrity and pheromone response MAPK cascades, as well as osmosensory signaling, glycerol metabolism, and asexual reproduction. It is linked to the regulation of ascospore formation, filamentous growth, and cell wall organization. Phenotypic associations include increased sporulation, altered mating efficiency, increased adhesion, and increased acquired thermotolerance, alongside absent hyperosmotic stress resistance and desiccation resistance. The gene product localizes to the cytoplasm, cell tip, and division septum. Studies of related genes in other species link the family to pathogenicity and stress responses.