ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_09931) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a lipid A export ATP-binding/permease MsbA-like protein, a member of the ABC transporter family with ATP-binding and transmembrane domains. The gene is associated with ABC-type oligopeptide transporter activity, ATP-coupled transmembrane transport, and ATP hydrolysis. It is linked to host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, secondary metabolism, signal transduction, siRNA-mediated post-transcriptional gene silencing, and retrotransposition. The product localises to the mitochondrial inner membrane and plasmalemma. Phenotypic associations include altered oxidative and osmotic stress resistance, abnormal vacuolar morphology and distribution, increased pexophagy, decreased endocytosis, abnormal cell cycle progression, and changes in fermentative metabolism and entry into stationary phase.