DSPC — Magnaporthe oryzae 70-15

Summary

MoDSPC (MGG_09700) in Magnaporthe oryzae 70-15 on chromosome 4 encodes a dual-specificity phosphatase (DUSP12 family) with protein tyrosine/serine/threonine phosphatase activity (EC 3.1.3.48). The product is associated with regulation of ribosome biogenesis, cytosolic large ribosomal subunit assembly, conidia formation, sporulation, and signaling. It localises to both the cytosol and nucleus. The gene is linked to blast disease in rice (Oryza sativa). Associations with delayed sporulation, abnormal spore wall formation, altered vegetative growth, increased ionic and hyperosmotic stress resistance, decreased cell death, and abnormal cytoskeleton morphology have been reported. Studies of related genes in other species connect the family to meiosis, acid pH resistance, and oxidative stress response, though these are not established for MoDSPC itself.