CHS1 — Magnaporthe oryzae 70-15

Summary

MoCHS1 (MGG_09551) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16), containing chitin synthase and nucleotide-diphosphosugar transferase domains. The gene is associated with cell septum assembly, septum positioning, ascospore wall assembly, appressorium formation, host invasion, septum digestion after cytokinesis, mitotic exit, chitin anabolism, nuclear division, conidia formation, cytokinesis, cell wall organization, invasive growth, hyphal growth, and cell cycle. It is linked to chitosome, hyphal tip, cross wall, cell periphery, and plasmalemma localization. Phenotypic associations include absent septum formation, abnormal lifespan, decreased flocculation, absent cell fusion, decreased adhesion, abnormal chitin deposition, and abnormal spore wall formation. Studies of related genes in other species link the family to polysaccharide content and decreased septum formation.