ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_08970) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a leptomycin B resistance protein pmd1, an ABC-type oligopeptide transporter with ATP-coupled transmembrane transporter activity and ATP hydrolase activity. The protein is localised to the mitochondrial inner membrane, plasmalemma and membrane. MoABC2 is associated with host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, secondary metabolism, signal transduction, siRNA-mediated post-transcriptional gene silencing, transposition, retrotransposition, translation elongation, oligopeptide export from mitochondria, regulation of cell growth, membrane transport and homeostasis. Phenotypic associations include abnormal cell cycle progression, decreased endocytosis, altered vacuolar morphology and distribution, increased pexophagy, abnormal nuclear export, altered colony colour, and changes in stress resistance, protein accumulation and fermentative metabolism.