CUT1 — Magnaporthe oryzae 70-15

Summary

MGG_02393 (CUT1) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a cutinase, a member of the cutinase/axe and AB_hydrolase families, with cutinase, lipase and carboxylesterase activities (EC 3.1.1.74). The gene is associated with appressorium-mediated host invasion, host invasion, sporulation, lipolysis and carbohydrate breakdown, and its product is localised extracellularly. It is linked to the related genes cutA, cut1 and pbc1. Studies of related genes in other species connect cutinase homologues to loss of pathogenicity, though some show unaffected pathogenicity, and to diseases such as grey mold and light leaf spot in diverse hosts including Brassica napus, tomato and Verticillium dahliae.