MYO1 — Magnaporthe oryzae 70-15

Summary

MGG_00748 (MYO1) in Magnaporthe oryzae 70-15 encodes a protein with myosin head motor, SH3, and other domains, and is annotated with microfilament motor activity, F-actin binding, hydrolase activity, and ATP binding. The gene is associated with cell motility, endocytosis, exocytosis, cytokinesis, autophagy, hyphal growth, asexual reproduction, pigmentation, host invasion, and actin filament organization. The product localizes to the actin cytoskeleton, hyphal tip, cross wall, actin patch, cell tip, and plasmalemma. MYO1 is linked to turgor pressure and numerous phenotypes including abnormal filamentous growth, absent spore germination, sterile mating, decreased endocytosis and cytokinesis rates, delayed autophagy, abnormal budding patterns, and altered prion inheritance. Related genes in other species connect it to potassium concentration and interactions with genes such as ATG40, LAS17, and VPS13.