MRM1 — Magnaporthe oryzae 70-15

Summary

MGG_00735 (MoMRM1) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a mitochondrial rRNA methyltransferase 1, possessing rRNA (guanine-N1-)-methyltransferase activity and RNA binding. The gene is associated with rRNA modification, mitochondrial RNA processing, mitochondrial translation elongation, oxidative phosphorylation, and mitochondrial large ribosomal subunit assembly. It localises to the mitochondrial lumen. Phenotypic associations link MoMRM1 to the absence of spore wall formation and invasive growth, abnormal mitochondrial morphology, decreased carbon source utilisation and desiccation resistance, and normal or decreased RNA accumulation. Studies of related genes in other species connect the family to oxidative stress response, respiratory growth, and stress resistance traits, including altered UV, hyperosmotic, and oxidative stress resistance, as well as decreased chronological lifespan and competitive fitness.