rga2 — Fusarium odoratissimum str. race 4

Summary

FOC4_G10011225 (rga2) in Fusarium odoratissimum str. race 4 encodes a Rho GTPase-activating protein (RhoGAP) containing a RhoGAP domain and is annotated with GAP activity, phosphoinositide binding, and lipid binding. This gene is associated with the regulation of fungal-type cell wall 1,3-alpha-glucan anabolism, small GTPase-mediated signal transduction, and cytoskeleton organization. The encoded product localizes to the cellular bud, growing cell tip, site of polarized growth, cell cortex, cell division site, plasmalemma, and the actomyosin contractile ring. Expression of rga2 is linked to responses to Congo Red and the fungal isolates NK51, BX51, NK27, and BX27 in the context of Fusarium oxysporum f. sp. cubense TR4. Studies of related genes in other species further connect the RhoGAP family to these processes.