SEC15 — Fusarium odoratissimum str. race 4

Summary

FoSEC15 (SEC15) encodes a protein containing EXOC6/Sec15 and Sec15_C domains. In Fusarium odoratissimum str. race 4, this gene is associated with exocytosis, Golgi to plasma membrane transport, protein secretion, and intracellular protein transport, and the product localizes to the exocyst. Phenotypic associations link FoSEC15 to abnormal sporulation, filamentous growth, and vesicle distribution; delayed autophagy, protein transport, and meiosis; increased mating efficiency and anaerobic growth; altered cell cycle progression, including M phase acceleration and metaphase-anaphase delay; and absent desiccation resistance and budding. The gene is also connected to the fungal pathogen Fusarium oxysporum f. sp. cubense TR4. Studies of related genes in other species link the family to decreased pexophagy.