laeA — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G19741, designated laeA on Fusarium graminearum PH-1 chromosome 3, encodes a protein belonging to the SAM-dependent methyltransferase superfamily and . The gene is associated with regulation of secondary metabolism, sterigmatocystin metabolism, positive regulation of penicillin metabolism, penicillin metabolism, positive regulation of ascospore formation, positive regulation of sterigmatocystin biosynthetic process, activation of gliotoxin anabolism, regulation of secondary metabolite biosynthesis, ascospore formation, secondary metabolism, spore formation, ergosterol anabolism, secondary metabolite biosynthesis, methylation, DNA-dependent transcription, disruption of host phagocytosis, and interaction with host, and is localized to the nucleus. Studies of related genes in other species link them to methyltransferase activity (EC 2.1.1.-).