BLM3 — Fusarium graminearum PH-1

Summary

FgBLM3 (FGRAMPH1_01G20251) on chromosome 3 of Fusarium graminearum PH-1 encodes a protein containing PSME4, HEAT_PSME4, Blm10_mid, Blm10_N, PSME4_C and ARM-type_fold domains. The gene is associated with proteasome degradation, proteasome assembly, and nuclear import. Phenotypic associations include abnormal peroxisomal distribution and morphology, absent mitophagy and nucleophagy, delayed cell cycle progression (G1 and G2/M phases), abnormal cytokinesis, increased cell death, decreased apoptosis, increased survival and lifespan in stationary phase, altered respiratory metabolism and small molecule transport, decreased iron and nitrogen source utilization, increased hyperosmotic stress resistance, decreased acquired thermotolerance, and increased prion formation.