RPL3 — Fusarium graminearum PH-1

Summary

FgRPL3 (FGRAMPH1_01G19953) on chromosome 3 of Fusarium graminearum PH-1 encodes a structural constituent of the ribosome, specifically a ribosomal uL3 domain protein that binds RNA. This gene is associated with translation, cytoplasmic translation, translational elongation, maintenance of translational fidelity, ribosomal large subunit assembly, ribosome assembly, and rRNA processing. It localizes to the cytosolic large ribosomal subunit, preribosome, SSU processome, cytosol, and fungal biofilm matrix. Phenotypic associations include abnormal cell cycle progression through G1/S and G2/M phase transitions, arrested G2 phase, delayed cytokinesis, premature apoptosis, absent entry into G0, increased chemical compound accumulation, increased carbon source utilization, absent anaerobic growth, decreased pheromone sensitivity, absent adhesion, and increased X-ray resistance. Related genes in other species are linked to protein content and oxidative stress response.

Annotations

Chromosome
3
Related genes
RDN37-2, RPL3, YCR016W, HAS1, DBP6, RPP0, RSA4, BTT1
GO terms
protein synthesis, RNA Binding, Cytosol, Ribosomal Large Subunit Assembly, Preribosome, RRNA Processing, cell bound, Translation
Publications
19214209, 34849884, 27594683, 27458021, 22515269, 9891066, 28450395, 9482897
Traits
RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, UTILIZATION OF CARBON SOURCE: INCREASED RATE, RESISTANCE TO CHEMICALS: NORMAL