BCK1 — Fusarium graminearum PH-1

Summary

FgBCK1 (FGRAMPH1_01G20041) on chromosome 3 of Fusarium graminearum PH-1 encodes a protein with a MAP kinase kinase kinase domain, protein kinase activity, MEKK activity, protein serine/threonine kinase activity, and ATP binding. The gene is associated with the cell integrity MAPK cascade, JNK cascade, p38 cascade, pheromone response MAPK cascade, fungal-type cell wall organization or biogenesis, sexual reproduction, conidia formation, spore formation, cell division, and activation of mitotic division septum assembly. The product localizes to the cell tip, division septum, cytoplasm, cytosol, plasmalemma, and spindle pole bodies. Related genes in other species are linked to reduced virulence, loss of pathogenicity, and hypervirulence, as well as associations with plant diseases such as rice blast, vascular wilt, and canker.