NDK1 — Fusarium graminearum PH-1

Summary

FgNDK1 (FGRAMPH1_01G19191) on chromosome 3 of Fusarium graminearum PH-1 encodes a nucleoside diphosphate kinase with nucleoside diphosphate kinase activity, ATP binding, and metal binding. The gene is associated with nucleoside triphosphate, UTP, CTP, and GTP anabolism, as well as anisotropic cell growth, sexual reproduction, secretion, detoxification, electron transfer, DNA damage response, and localization. It localizes to the cytosol, nucleus, mitochondrial envelope lumen, and extracellular space. Phenotypic associations include arrested or decreased vegetative growth, abnormal mitochondrial and lipid particle morphology, increased mutation frequency and colony sectoring, increased cold and heat sensitivity, decreased respiratory growth and starvation resistance, altered protein accumulation, and increased killer toxin and chemical resistance. Related genes in other species are linked to germination rate.