HIS3 — Fusarium culmorum CS7071

Summary

FCUL_08269.1 (HIS3) on chromosome 3 of Fusarium culmorum encodes an imidazoleglycerol-phosphate dehydratase. The gene is associated with histidine anabolism and the response to histidine, as well as with a wide range of other processes including appressorium formation, fatty acid transport, recombinational repair, mating type switching, retrotransposition, and pheromone response. Studies of related genes in other species link the family to loss of pathogenicity and to traits such as protein content, salt tolerance, and oxidative stress, though these associations are not yet established in F. culmorum. The protein belongs to the imidazoleglycerol-phosphate dehydratase family and contains a ribosomal S5 D2-type fold domain.