ACT — Fusarium culmorum CS7071

Summary

FCUL_10463.1, designated ACT1 on chromosome 4 of Fusarium culmorum, encodes a protein that is a structural constituent of the cytoskeleton and possesses ATP-binding and hydrolase activities. The gene is associated with a wide range of cellular processes including actin depolymerization, cytokinesis, polar cell growth, filamentous growth, cell morphogenesis, protein secretion, vacuole fusion, nuclear movement, pinocytosis, and cytoskeleton organization. It is linked to localization at the actin cytoskeleton, F-actin, the actomyosin contractile ring, the hyphal tip, and the perinuclear region. Studies of related genes in other species connect the family to reduced virulence, as well as associations with sugar content, salt sensitivity, and oxidative stress.