FBP1 — Fusarium culmorum CS7071

Summary

FCUL_11735.1 (FBP1) on chromosome 4 of Fusarium culmorum encodes a fructose 1,6-bisphosphate 1-phosphatase, a class-1 FBPase with N-terminal and C-terminal domains that binds metal ions. This gene is associated with gluconeogenesis, fructose 1,6-bisphosphate metabolism, and fructose 6-phosphate metabolism, as well as sucrose and uracil anabolism. It is linked to cellular response to glucose starvation, catabolite repression, cAMP signaling, adenylyl cyclase activation, and regulation of cell growth. Additional associations include the glyoxylate cycle, fatty acid beta-oxidation, sexual reproduction, and mRNA and lncRNA transcription. The gene product localises to the cytoplasm, cytosol, and nucleus. Studies of related genes in other species link the FBP1 family to oxidative stress.