ATB2 — Fusarium culmorum CS7071

Summary

FCUL_00432.1 (TUB1) on chromosome 1 of Fusarium culmorum encodes a structural constituent of the cytoskeleton, belonging to the alpha-tubulin and tubulin/FtsZ GTPase superfamilies. The protein exhibits GTP binding and hydrolase activity, and is a core component of the tubulin complex, localizing to microtubules, the spindle, astral microtubules, the cytoplasm, and the nucleus. TUB1 is associated with microtubule-based processes, including microtubule cytoskeleton organization and assembly, nuclear migration via microtubule-mediated pushing forces, and nuclear division. It is also linked to ascospore formation, the mitotic and meiotic cell cycles, and metal binding. Studies of related genes in other species link the family to GTPase activity (EC 3.6.5.-).