RPB2 — Fusarium culmorum CS7071

Summary

FCUL_02745.1 (RPB2) on Fusarium culmorum chromosome 1 encodes a DNA-directed RNA polymerase subunit, possessing DNA-directed RNA polymerase, RdRP, ribonucleoside, RNA, DNA, and zinc-binding activities. The product is a component of RNA polymerase I, II, and III complexes, localizing to the nucleus, cytosol, mitochondria, chromatin, and centric heterochromatin. This gene is associated with transcription initiation and elongation from Pol I and Pol II promoters, Pol III transcription termination, mRNA transcription, DNA-dependent transcription, RNAi-mediated heterochromatin assembly, global genome and transcription-coupled nucleotide excision repair, RNA breakdown, translation elongation, and proteolysis. It is also linked to seed germination and chlamydospore formation. Studies of related genes in other species connect the RPB2 family to RNA polymerase activity (EC 2.7.7.6).