AREA — Fusarium culmorum CS7071

Summary

FCUL_04465.1 (AREA) on chromosome 2 of Fusarium culmorum encodes a GATA-family transcription factor with DNA-binding transcription activator and repressor activity specific to RNA polymerase II, and contains a zinc-binding domain. The gene is associated with the regulation of nitrogen utilization, nitrate assimilation, and amide breakdown, as well as arginine metabolism. It is linked to photosynthesis, chlorophyll fluorescence, and autotrophy, and to traits including deoxynivalenol content, photosynthetic rate, plant height, quantum yield, and respiration rate. Additional associations include mycotoxin and ergosterol anabolism, secondary metabolism, sporulation, and negative regulation of conjugation induction. The protein localizes to the nucleus, cytoplasm, cytosol, and cell division site. Studies of related genes in other species link the AREA family to leaf nitrogen content, leaf area, root length, and grain weight, as well as to reduced virulence.