ERG6 — Fusarium culmorum CS7071

Summary

FCUL_04845.1 (ERG6) on chromosome 2 of Fusarium culmorum encodes a sterol 24C methyltransferase. The enzyme is associated with ergosterol anabolism and metabolism, methylation, and demethylation. It has been linked to membrane hyperpolarization, lipophagy, lipolysis, vacuolar localization and fusion, spore germination, glucose import, mitotic recombination, the pentose-phosphate shunt, signal transduction, secretion, fermentation, and hypersensitivity. The protein localizes to the adiposome, endoplasmic reticulum, and mitochondria. Studies of related genes in other species link the family to reduced virulence, cell membrane stability, oxidative stress, and oleic acid content.