ERG4 — Fusarium culmorum CS7071
Summary
FCUL_03040.1 (ERG4) on chromosome 1 of Fusarium culmorum encodes a protein with D24(24-1)-sterol reductase and D14-sterol reductase activities, and NADP binding. The gene is associated with ergosterol and sterol anabolism, and localises to the endoplasmic reticulum membrane. It is linked to spore germination, hyphal and filamentous growth, cell wall assembly, cell polarization, invasive growth, mating, fermentation, and hypersensitivity. Studies of related genes in other species connect the ERG4 family to reduced virulence and salt tolerance.
Annotations
- Chromosome
- 1
- Related genes
- ERG4, TRP1, SCS7, ERG1, ERG2, ERG26, HAL5, OCH1
- GO terms
- D24(24-1)-sterol reductase activity, D24-sterol reductase activity, ER membrane, ergosterol anabolism, ER, NADP Binding, Cellular Response To Xenobiotic Stimulus, D14-sterol reductase activity
- Publications
- 27216456, 32737079, 28559891, 10233147, 9339899, 28768829, 11025657, 9427410
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, RESISTANCE TO CHEMICALS: NORMAL, CELL SIZE: INCREASED, RESPIRATORY GROWTH: INCREASED