NAG1 — Fusarium culmorum CS7071

Summary

FCUL_04199.1 (NAG1) on chromosome 2 of Fusarium culmorum encodes a glucosamine-6-phosphate deaminase, an enzyme that also exhibits identical protein binding activity. The gene is associated with the breakdown of N-acetylneuraminate, glucosamine, and N-acetylglucosamine, as well as with secretion, secondary metabolism, carbohydrate metabolism, filamentous growth, and filamentous growth in response to biotic stimulus. It is also linked to translation and localises to the cytoplasm. The encoded protein belongs to the Glucosamine6P_isomerase and NagB/RpiA_transferase-like families. NAG1 is associated with glucose content. Studies of related genes in other species link the family to reduced virulence.

Annotations

Chromosome
2
Related genes
NAG1
GO terms
protein synthesis, Secretion, Cytoplasm, N-acetylneuraminate breakdown, Glucosamine-6-phosphate Deaminase Activity, Identical Protein Binding, Filamentous Growth, N-acetylglucosamine breakdown
Publications
PMID:20109094, PMID:38025898, PMID:18675351, PMID:12788701, PMID:17419877, PMID:11114181, PMID:12589826, PMID:11705974
Traits
reduced virulence, glucose content