GANB — Fusarium culmorum CS7071

Summary

FCUL_11370.1 (symbol GPA2) on chromosome 4 of Fusarium culmorum encodes a G-protein alpha subunit, as indicated by its GproteinA_insert, Fungi_Gprotein_alpha, and Gprotein_alpha_su domains. The product exhibits GTPase activity, GTP binding, and G protein-coupled receptor binding, and is a component of the heterotrimeric G-protein complex. This gene is associated with GPCR signaling, adenylyl cyclase activation, cAMP anabolism and signaling, the MAPK cascade, and protein kinase A signaling. It is linked to glucose detection and import, response to glucose and nutrients, conidia formation, hyphal growth, pheromone response and conjugation, pexophagy, and nuclear import. Studies of related genes in other species connect the family to loss of pathogenicity, reduced virulence, germination rate, protein content, and oxidative stress.