BML — Fusarium culmorum CS7071

Summary

FCUL_11457.1, symbol TUB2 on chromosome 4 of Fusarium culmorum, encodes a beta-tubulin protein that is a structural constituent of the cytoskeleton and possesses GTPase activity and GTP binding. This gene is associated with microtubule-based processes, including microtubule cytoskeleton organization, microtubule shortening and dynamics, spindle assembly and elongation, chromosome separation, nuclear division, and mitotic prophase and anaphase. It is also linked to the mitotic cell cycle, spindle assembly checkpoint, nuclear movement, and response to antibiotic. The encoded protein localizes to the microtubule and cytoplasm. Studies of related genes in other species link the TUB2 family to reduced virulence and unaffected pathogenicity, though these associations are not established for F. culmorum itself.