NMR — Fusarium culmorum CS7071

Summary

FCUL_10316.1 (symbol nmr) on Fusarium culmorum chromosome 4 encodes a protein with NADP+, NAD+ and NAD binding and redox activity, belonging to the NmrA-like oxidoreductase family. This gene is associated with nitrogen catabolite repression of transcription from RNA polymerase II promoters and regulation of nitrogen utilization, as well as downregulation of transcription, spore germination, biofilm formation, fermentation, translation, and cell growth. The encoded protein localizes to the cytoplasm and nucleus. It has also been linked to oxidative stress. Studies of related genes in other species link this family to oxidoreductase activity (EC 1.5.1.- and EC 1.-.-.-).