BRN1 — Fusarium culmorum CS7071

Summary

FCUL_10214.1 (BRN1) on chromosome 4 of Fusarium culmorum encodes a protein with chromatin-binding activity, belonging to the condensin barren/su2 domain family. The gene is associated with fundamental cell cycle processes including mitosis, chromosome condensation, spindle assembly, and chromosome segregation, as well as DNA replication and repair. BRN1 is associated with melanin biosynthesis. The encoded protein localises to the condensin complex, chromatin, heterochromatin, and the nucleus. Studies of related genes in other species, such as YBL097W and cnd2, connect the family to condensin function and mitotic chromosome dynamics.