ERG6 — Fusarium culmorum CS7071

Summary

FCUL_07924.1 (ERG6) on Fusarium culmorum chromosome 3 encodes a sterol 24C methyltransferase. The enzyme is associated with ergosterol metabolism and anabolism, methylation and demethylation processes, and is linked to membrane hyperpolarization, lipophagy, lipolysis, vacuole fusion and localization, spore germination, glucose import, mitotic recombination, the pentose-phosphate shunt, signal transduction, secretion, fermentation, and hypersensitivity. The gene product localizes to the adiposome, endoplasmic reticulum, mitochondria, and nucleus. Studies of related genes in other species link the family to reduced virulence, cell membrane stability, oxidative stress, and oleic acid content.