HSP98 — Candida albicans

Summary

CR_08250C_A (HSP98, also known as HSP104) in Candida albicans encodes a protein with ATP-dependent protein disaggregase activity, misfolded protein binding, chaperone protein binding, ADP binding, identical protein binding, and ATP hydrolase activity. This gene is associated with cellular thermotolerance, response to heat, stress granule disassembly, protein stabilization and refolding, protein unfolding, translation termination, quorum sensing, sumoylation, nucleocytoplasmic transport, mycose metabolism, iron transport, cell cycle control, and biofilm formation. It localizes to the cytoplasm, cytosol, nucleus, nuclear periphery, nuclear envelope, protein aggregate center, and mitochondrial lumen. Phenotypic associations include abnormal chemical compound excretion, nitrogen source utilization, protein activity, prion inheritance and formation, biofilm formation, cell fusion, and anaerobic growth, with normal vegetative growth and acquired thermotolerance.