LIP4 — Candida albicans

Summary

Candida albicans gene LIP4 (also known as CaTRI8 or TRI8) on chromosome 6 encodes a secreted lipase belonging to the AB hydrolase family, with confirmed lipase and triacylglycerol lipase (EC 3.1.1.3) activity. The gene is associated with host invasion, immune response, biofilm formation, filamentous growth in response to starvation and biotic stimulus, mating, secretion, cellular response to starvation, lipolysis, and extracellular localisation. The gene is also associated with LIP2, LIP8, LIP1, LIP9, LIP7, LIP6, and TRI8. Related genes in other species, including Fusarium oxysporum strains, share sequence similarity with LIP4.