GAL4 — Candida albicans

Summary

C2_10590W_A (GAL4) on Candida albicans chromosome 2 encodes a DNA-binding transcription factor with a Zn2Cys6 DNA-binding domain and a Gal4 dimerisation domain, acting as a sequence-specific DNA-binding protein that regulates RNA polymerase II transcription. The gene is associated with galactose metabolism, the Leloir pathway, and upregulation of glycolysis, as well as carbon catabolite activation of transcription and the glucose effect. It is also linked to cell wall biogenesis, biofilm formation, hyphal growth, filamentous growth, invasive growth, cell adhesion, fermentation, signal transduction, and hypersensitivity. The product localises to the nucleus. Related genes in other species include LAC9.