NGT1 — Candida albicans

Summary

NGT1 (C3_00650W_A) in Candida albicans encodes a protein with D-GlcNAc transmembrane transporter activity and transmembrane transporter activity, belonging to the UNC-93-like regulator and major facilitator superfamily (MFS) domains. It is associated with N-acetylglucosamine transport, metabolism, and breakdown, as well as glycan biosynthesis, carbohydrate metabolism, and membrane transport. The gene is linked to hyphal growth, filamentous growth, phenotypic switching, cell morphogenesis, phagocytosis, mating, endocytosis, cell death, and pH reduction. It localizes to the plasma membrane and cytoplasm. Related genes in other species connect the family to similar transport and regulatory functions, though these associations are not established for NGT1 itself.