MCB — Candida albicans
Summary
C2_01110C_A (MCB, also known as BCY1) in Candida albicans encodes a protein with cAMP-dependent protein kinase regulator activity, cAMP binding, PKA catalytic subunit binding, and cAMP-dependent protein kinase inhibitor activity. This gene is associated with nutrient storage, downregulation of nuclear division, regulation of cytoplasmic mRNA processing body assembly, downregulation of Ras protein signal transduction, regulation of cell differentiation, positive regulation of asexual sporulation resulting in formation of a cellular spore, glycogen metabolism, protein localization to bud neck, cell aggregation, upregulation of protein export from nucleus, germ tube formation, tube formation, adenylate cyclase-activating GPCR signaling pathway, asexual sporulation resulting in formation of a cellular spore, cellular response to nitrogen starvation, cell differentiation, cellular response to stress, and response to starvation. It is linked to vacuolar transport, filamentous growth, cell cycle progression through G2/M phase, protein/peptide distribution, prion inheritance, budding rate, virulence, polyploidy, aneuploidy, cell cycle progression in anaphase, spore germination, fermentative growth, prion loss, adhesion, pexophagy, mutation frequency, cell cycle passage through start, meiosis, chromosome segregation, respiratory metabolism, colony color, protein activity, vesicle distribution, and desiccation resistance. The encoded protein localises to the cAMP-dependent protein kinase complex, P-bodies, stress granules, vacuolar membrane, chromatin
Annotations
- Chromosome
- 2
- Related genes
- MCB, mcb, MAF1, ZDS1, SLT2, MCD1, SPC24, DAM1
- GO terms
- NO storage, Cell Cycle, Sexual Reproduction, cell physiology, Cell Growth, Biofilm Formation, Germ Tube Formation, G1 Phase
- Publications
- 19822674, 28383696, 27163342, 32737079, 22445487, 22496512, 19299562, 19302420
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, NUCLEAR POSITION: ABNORMAL, ENTRY INTO G0 (STATIONARY PHASE): INCREASED