STP2 — Candida albicans

Summary

C1_13350W_A, the STP2 gene on chromosome 1 of Candida albicans, encodes a C2H2 zinc-finger transcription factor with DNA-binding and transcription coactivator activity. The product localises to the nucleus, cytoplasm and plasma membrane. STP2 is associated with the regulation of arginine and amino acid metabolism, hexose breakdown, N-acetylglucosamine metabolism, the shikimate pathway, and responses to pH, amino acid starvation, and oxidative stress. It is linked to germ tube formation, filamentous growth, and innate immunity. Related genes in other species link the family to increased virulence.